Traumatic axonal injury of the corticospinal tract in the subcortical white matter in patients with mild traumatic brain injury

Title
Traumatic axonal injury of the corticospinal tract in the subcortical white matter in patients with mild traumatic brain injury
Author(s)
장성호서정표
Keywords
TRACTOGRAPHY; STIMULATION; MULTICENTER; IMPAIRMENT; RECOVERY; HUMANS
Issue Date
201501
Publisher
INFORMA HEALTHCARE
Citation
BRAIN INJURY, v.29, no.1, pp.110 - 114
Abstract
Background: Little is known about injury of the corticospinal tract (CST) in patients with mild traumatic brain injury (TBI). This study reports on patients with mild TBI who showed traumatic axonal injury of the CST in the sub-cortical white matter, as demonstrated by diffusion tensor tractography (DTT). Methods: Four patients with mild TBI who complained of motor weakness and had DTT parameters within the normal range, including fractional anisotropy, apparent diffusion coefficient and fibre number of the CST, and 10 normal control subjects were recruited for this study. Results: All four patients showed partial tearing of the CSTs in a portion of the sub-cortical white matter in both hemispheres on DTT. However, three patients showed low amplitude on motor evoked potential obtained from both hand muscles by transcranial magnetic stimulation and two patients revealed abnormality of hand motor function in terms of grip strength or Purdue Pegboard score. Conclusions: This study demonstrated traumatic axonal injury of the CST using configurational evaluation of DTT in patients with mild TBI. It is believed that configurational evaluation using DTT would be a useful technique for detection of localized traumatic axonal injury in patients with mild TBI.
URI
http://hdl.handle.net/YU.REPOSITORY/33684http://dx.doi.org/10.3109/02699052.2014.973447
ISSN
0269-9052
Appears in Collections:
의과대학 > 재활의학교실 > Articles
의과대학 > 영상의학과학교실 > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE