Case Characteristics, Hyperacute Treatment, and Outcome information from the Clinical Research Center for Stroke-Fifth Division Registry in South Korea

Title
Case Characteristics, Hyperacute Treatment, and Outcome information from the Clinical Research Center for Stroke-Fifth Division Registry in South Korea
Author(s)
이준Beom Joon Kim[Beom Joon Kim]Jong-Moo Park[Jong-Moo Park]Kyusik Kang[Kyusik Kang]Soo Joo Lee[Soo Joo Lee]Youngchai Ko[Youngchai Ko]Jae-Kwan Cha[Jae-Kwan Cha]Dae-Hyun Kim[Dae-Hyun Kim]Moon-Ku Han[Moon-Ku Han]Hee-Joon Bae[Hee-Joon Bae]
Keywords
ACUTE ISCHEMIC-STROKE; TISSUE-PLASMINOGEN ACTIVATOR; GUIDELINES-STROKE; ENDOVASCULAR TREATMENT; TEMPORAL TRENDS; INTRAVENOUS THROMBOLYSIS; RECURRENT STROKE; TRIAL; RISK; THROMBECTOMY
Issue Date
201501
Publisher
KOREAN STROKE SOC
Citation
JOURNAL OF STROKE, v.17, no.1, pp.38 - 53
Abstract
Characteristics of stroke cases, acute stroke care, and outcomes after stroke differ according to geographical and cultural background. To provide epidemiological and clinical data on stroke care in South Korea, we analyzed a prospective multicenter clinical stroke registry, the Clinical Research Center for Stroke-Fifth Division (CRCS-5). Patients were 58% male with a mean age of 67.2 +/- 12.9 years and median National Institutes of Health Stroke Scale score of 3 [1-8] points. Over the 6 years of operation, temporal trends were documented including increasing utilization of recanalization treatment with shorter onset-to-arrival delay and decremental length of stay. Acute recanalization treatment was performed in 12.7% of cases with endovascular treatment utilized in 36%, but the proportion of endovascular recanalization varied across centers. Door-to-IV alteplase delay had a median of 45 [33-68] min. The rate of symptomatic hemorrhagic transformation (HT) was 7%, and that of any HT was 27% among recanalization-treated cases. Early neurological deterioration occurred in 15% of cases and were associated with longer length of stay and poorer 3-month out-comes. The proportion of mRS scores of 0-1 was 42% on discharge, 50% at 3 months, and 55% at 1 year after the index stroke. Recurrent stroke up to 1 year occurred in 4.5% of patients; the rate was higher among older individuals and those with neurologically severe deficits. The above findings will be compared with other Asian and US registry data in this article.
URI
http://hdl.handle.net/YU.REPOSITORY/33669http://dx.doi.org/10.5853/jos.2015.17.1.38
ISSN
2287-6391
Appears in Collections:
의과대학 > 신경과학교실 > Articles
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