Ultrasonics in isocyanide-based multicomponent reactions: A new, efficient and fast method for the synthesis of fully substituted 1,3,4-oxadiazole derivatives under ultrasound irradiation

Title
Ultrasonics in isocyanide-based multicomponent reactions: A new, efficient and fast method for the synthesis of fully substituted 1,3,4-oxadiazole derivatives under ultrasound irradiation
Author(s)
주상우Morteza Rouhani [Morteza Rouhani ]Ali Ramazani[Ali Ramazani]
Keywords
ONE-POT SYNTHESIS; STABILIZED PHOSPHORUS YLIDES; SOLVENT-FREE CONDITIONS; POLYMER-SUPPORTED REAGENTS; AZA-WITTIG REACTION; SILICA-GEL; HETEROCYCLIC-COMPOUNDS; SONOCHEMICAL SYNTHESIS; DRUG DISCOVERY; DIALKYL
Issue Date
201501
Publisher
ELSEVIER SCIENCE BV
Citation
ULTRASONICS SONOCHEMISTRY, v.22, pp.391 - 396
Abstract
A fast and convenient approach to the synthesis of fully substituted 1,3,4-oxadiazoles via three-component reaction of aromatic carboxylic acids, acenaphthoquinone, and (N-isocyanimino)triphenylphosphorane under ultrasound irradiation is described. Furthermore, a series of compounds were synthesized and characterized by melting point, IR, NMR and MS. Utilization of easy reaction conditions, very high to excellent yields, and short reaction times makes this manipulation potentially very useful. (C) 2014 Elsevier B.V. All rights reserved.
URI
http://hdl.handle.net/YU.REPOSITORY/33660http://dx.doi.org/10.1016/j.ultsonch.2014.06.017
ISSN
1350-4177
Appears in Collections:
공과대학 > 기계공학부 > Articles
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