Mild and Efficient One-Pot Synthesis of Diverse Flavanone Derivatives via an Organocatalyzed Mannich-Type Reaction

Title
Mild and Efficient One-Pot Synthesis of Diverse Flavanone Derivatives via an Organocatalyzed Mannich-Type Reaction
Author(s)
이용록부팔라파티나가바산타스리니바수하립개나우샤드에다야둘라
Keywords
PYRANOCHALCONE NATURAL-PRODUCTS; REDUCTASE INHIBITORY-ACTIVITY; CONCISE TOTAL-SYNTHESIS; ALDOSE REDUCTASE; ALPHA,BETA-UNSATURATED ALDEHYDES; CHEMICAL-CONSTITUENTS; BREAST-CANCER; STRUCTURAL REQUIREMENTS; PRENYLATED FLAVANONES; BIOLOGICAL EVALUATION
Issue Date
201402
Publisher
GEORG THIEME VERLAG KG
Citation
SYNTHESIS-STUTTGART, v.46, no.4, pp.465 - 474
Abstract
A facile ethylenediamine diacetate (EDDA)-catalyzed one-pot synthesis of biologically interesting flavanone derivatives from 2-hydroxyacetophenones, aromatic aldehydes, and aniline via a Mannich-type reaction is described. This synthetic method provides a rapid access to biologically interesting flavanone derivatives. To demonstrate this method, several biologically interesting natural products bearing a flavanone moiety were synthesized as racemates.
URI
http://hdl.handle.net/YU.REPOSITORY/33348http://dx.doi.org/10.1055/s-0033-1340466
ISSN
0039-7881
Appears in Collections:
공과대학 > 화학공학부 > Articles
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