Efficient one-pot synthesis of novel and diverse tetrahydroquinolines bearing pyranopyrazoles using organocatalyzed domino Knoevenagel/hetero Diels-Alder reactions

Title
Efficient one-pot synthesis of novel and diverse tetrahydroquinolines bearing pyranopyrazoles using organocatalyzed domino Knoevenagel/hetero Diels-Alder reactions
Author(s)
이용록판딧라메쉬월프라사드
Keywords
INTRAMOLECULAR CYCLIZATION; ANTIINFLAMMATORY AGENTS; PYRAZOLE DERIVATIVES; ASYMMETRIC-SYNTHESIS; FACILE SYNTHESIS; INHIBITORS; PROTEIN; PYRANO; TETRAHYDROCHROMANOQUINOLINES; STREPTOMYCES
Issue Date
201402
Publisher
SPRINGER
Citation
MOLECULAR DIVERSITY, v.18, no.1, pp.39 - 50
Abstract
A new synthetic route to biologically interesting diverse tetrahydroquinolines bearing pyranopyrazoles was developed by reacting pyrazolones and ,-dialkylated aminobenzaldehydes in the presence of EDDA. The key strategy underlying the methodology used was the domino Knoevenagel/hetero Diels-Alder reaction. This synthetic method provides a variety of novel tetrahydroquinolines in good yields.
URI
http://hdl.handle.net/YU.REPOSITORY/33310http://dx.doi.org/10.1007/s11030-013-9482-6
ISSN
1381-1991
Appears in Collections:
공과대학 > 화학공학부 > Articles
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