Chitosan-Conjugated Dendritic Ag Nanopowders for Photothermal Therapy Applications

Title
Chitosan-Conjugated Dendritic Ag Nanopowders for Photothermal Therapy Applications
Author(s)
변정훈김영우[김영우]
Keywords
SILVER NANOSTRUCTURES; NANOPARTICLES; NANODENDRITES; CRYSTALLINE; IRRADIATION; GENERATION; PALLADIUM; GROWTH; ROUTE; AGENT
Issue Date
201402
Publisher
AMER CHEMICAL SOC
Citation
ACS MACRO LETTERS, v.3, no.2, pp.205 - 210
Abstract
We report the development of Ag nanodendrites where ultrafine Pd particles served as seeds for the subsequent deposition of Ag on their surfaces. By applying chitosan as both a reductant and a stabilizer, chitosan-conjugated Ag dendritic nanopowders were continuously synthesized using a serial system consisting of a spark discharge, an ultrasound-assisted polyol cell, and a collison atomizer with a heated tubular reactor. The resulting materials were then employed to kill cancerous cells photothermally. A spark discharge between Pd electrodes was employed to vaporize Pd components into a N-2 flow, and finally Pd particles were injected into an ultrasound irradiating Ag polyol cell to initiate Ag deposition on incoming Pd primary particles (similar to 4 nm in lateral dimension). The chitosan-conjugated Ag nanodendrites (similar to 240 nm in lateral dimension) were formed through collison atomization, and the nanodendrites were employed as sensitizers for photothermal cancerous cell killing under near-infrared irradiation in vitro.
URI
http://hdl.handle.net/YU.REPOSITORY/33129http://dx.doi.org/10.1021/mz500006k
ISSN
2161-1653
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공과대학 > 기계공학부 > Articles
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