Clinical Outcomes of the Endoscopic Submucosal Dissection of Early Gastric Cancer Are Comparable between Absolute and New Expanded Criteria

Title
Clinical Outcomes of the Endoscopic Submucosal Dissection of Early Gastric Cancer Are Comparable between Absolute and New Expanded Criteria
Author(s)
이시형신근영[신근영]전성우[전성우]조광범[조광범]김경옥장병익박경식[박경식]김은수[김은수]정은진[정은진]박창근[박창근]
Keywords
MUCOSAL RESECTION; RECURRENCE; SURGERY
Issue Date
201503
Publisher
EDITORIAL OFFICE GUT & LIVER
Citation
GUT AND LIVER, v.9, no.2, pp.181 - 187
Abstract
Background/Aims: Advances in endoscopic submucosal dissection (ESD) techniques have led. to the development of expanded criteria for endoscopic resection of early gastric cancer (EGC). The aim of this study was to evaluate the short- and long-term outcomes for ESD using indication criteria. Methods: A total of 1,105 patients underwent ESD for EGC at six medical centers. The patients were classified into the following two groups based on the lesion size, presence of ulceration and pathological review: an absolute criteria group (n=517) and an expanded criteria group (n=588). Results: The curative resection rates (91.1% vs 91.3%, p=0.896) were similar in the absolute criteria group and the expanded criteria group. The en bloc resection rates (93.4% and 92.3%, respectively; p=0.488) and complete resection rates (98.3% and 97.4%, respectively; p=0.357) did not differ between the groups. The cumulative disease-free survival rates and the overall survival rates were similar between the groups (p=0.778 and p=0.654, respectively). Independent factors for the curative resection of EGC included tumor location (upper vs middle and lower, 2.632 [1.128-6.144] vs 3.497 [1.560-7.842], respectively) and en bloc resection rate 12.576 [7.442-21.250]. Conclusions: The expanded criteria for ESD in cases of EGC is comparable with the widely accepted pre-existing criteria.
URI
http://hdl.handle.net/YU.REPOSITORY/33096http://dx.doi.org/10.5009/gnl13417
ISSN
1976-2283
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의과대학 > 내과학교실 > Articles
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