Engineering of a lipid-polymer nanoarchitectural platform for highly effective combination therapy of doxorubicin and irinotecan

Title
Engineering of a lipid-polymer nanoarchitectural platform for highly effective combination therapy of doxorubicin and irinotecan
Author(s)
김종오티르거네쉬라마사미루딸라히마빈두최주연트란탄힙김정환구세광[구세광]최한곤[최한곤]용철순
Keywords
DRUG-DELIVERY; EFFICACY; PH
Issue Date
201504
Publisher
ROYAL SOC CHEMISTRY
Citation
CHEMICAL COMMUNICATIONS, v.51, no.26, pp.5758 - 5761
Abstract
We developed a highly stable lipid-polymer nanoarchitectural platform for effective combination therapy of doxorubicin and irinotecan in the polyelectrolyte complex nanoparticle core, followed by incorporation of the whole assembly into a lecithin bilayer. It shows great potential for the treatment of a broad range of cancers.
URI
http://hdl.handle.net/YU.REPOSITORY/32854http://dx.doi.org/10.1039/c5cc00482a
ISSN
1359-7345
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약학대학 > 약학부 > Articles
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