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dc.contributor.author최혁재ko
dc.contributor.author최현규[최현규]ko
dc.contributor.author제인규[제인규]ko
dc.contributor.author김금진ko
dc.contributor.author김상현[김상현]ko
dc.contributor.author김정아[김정아]ko
dc.contributor.author이승호ko
dc.date.accessioned2015-12-17T04:54:57Z-
dc.date.available2015-12-17T04:54:57Z-
dc.date.created2015-11-13-
dc.date.issued201504-
dc.identifier.citationNATURAL PRODUCT COMMUNICATIONS, v.10, no.4, pp.631 - 632-
dc.identifier.issn1934-578X-
dc.identifier.urihttp://hdl.handle.net/YU.REPOSITORY/32749-
dc.description.abstractActivity-guided isolation of compounds from the fruits of Amomztm xanthioides resulted in the purification of fourteen phenolic compounds, 4-hydroxybenzaldehyde (1), 3,4-dihydroxybenzaldehyde (2), 3,5-dimethoxy-4-methylbenzaldehyde (3), syringic aldehyde (4), benzoic acid (5), 3,4-dihydroxy benzoic acid (6), vanillic acid (7), 3-hydroxy-2-methoxybenzoic acid (8), o-vanillic acid (9), phenylacetic acid (10), tyrosol (11), pyrocatechol (12), 1,2,4,5-tetramethoxybenzene (13), and 3,3',5,5'-tetramethoxybipheny1-4,4'-diol (14). To evaluate the anti-allergic inflammatory activities of these compounds, we examined the inhibitory effects of the isolates (1-14) on histamine release and on the expressions of tumor necrosis factor (TNF)-alpha and interleukin (IL)-6 genes by using human mast cells. Of the tested compounds, 9, 11, and 13 suppressed histamine release from mast cells, and all isolates attenuated the expressions of the pro-inflammatory cytokines, TNF-alpha and IL-6 genes in human mast cells.-
dc.language영어-
dc.publisherNATURAL PRODUCTS INC-
dc.subjectCYTOKINE PRODUCTION-
dc.subjectHISTAMINE-RELEASE-
dc.subjectGALLIC ACID-
dc.titleAnti-allergic Inflammatory Activities of Compounds of Amomi Fructus-
dc.typeArticle-
dc.identifier.wosid000353424800025-
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