Chemical constituents from the leaves of Juglans mandshurica

Title
Chemical constituents from the leaves of Juglans mandshurica
Author(s)
Da Lei Yao[Da Lei Yao]Chang Hao Zhang[Chang Hao Zhang]Jie Luo[Jie Luo]Mei Jin[Mei Jin]Ming Shan Zheng[Ming Shan Zheng]Jiong Mo Cui[Jiong Mo Cui]손종근Gao Li[Gao Li]
Keywords
STEM-BARK; ROOTS; DIARYLHEPTANOIDS; APOPTOSIS; CELLS; GLUCOSIDES; FRUIT; MAXIM; LEAF; ANTIOXIDANT
Issue Date
201504
Publisher
PHARMACEUTICAL SOC KOREA
Citation
ARCHIVES OF PHARMACAL RESEARCH, v.38, no.4, pp.480 - 484
Abstract
Two new (1 and 3) and two known diarylheptanoids (2 and 4), along with two tetralones (5 and 6), one naphthoquinone (7), four phenylpropanoids (8-11), and one phenol (12) were isolated from the leaves of Juglans mandshurica. Their structures were elucidated on the basis of spectral and chemical data. Compounds 2 and 10 are firstly isolated from this plant and 8 and 12 were isolated from the Juglans genus for the first time. Among these compounds, only 7 exhibited moderate cytotoxicities against cultured MGC-803, A549, K562, and HeLa tumor cell lines with IC50 values of 25.90, 28.60, 39.06, 44.90 mu M, respectively.
URI
http://hdl.handle.net/YU.REPOSITORY/32728http://dx.doi.org/10.1007/s12272-014-0398-1
ISSN
0253-6269
Appears in Collections:
약학대학 > 약학부 > Articles
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