Characteristics, In-Hospital and Long-Term Clinical Outcomes of Nonagenarian Compared with Octogenarian Acute Myocardial Infarction Patients

Title
Characteristics, In-Hospital and Long-Term Clinical Outcomes of Nonagenarian Compared with Octogenarian Acute Myocardial Infarction Patients
Author(s)
김영조이기홍[이기홍]안영근[안영근]김성수[김성수]류시현[류시현]정영욱[정영욱]장수영[장수영]조재영[조재영]정해창[정해창]박근호[박근호]
Keywords
PERCUTANEOUS CORONARY INTERVENTIONS; DENSITY-LIPOPROTEIN CHOLESTEROL; GREATER-THAN-OR-EQUAL-TO-90 YEARS; ELDERLY-PATIENTS; REGISTRY; AGE; ANGIOPLASTY; MANAGEMENT; MORTALITY; EVENTS
Issue Date
201404
Publisher
KOREAN ACAD MEDICAL SCIENCES
Citation
JOURNAL OF KOREAN MEDICAL SCIENCE, v.29, no.4, pp.527 - 535
Abstract
We compared clinical characteristics, management, and clinical outcomes of nonagenarian acute myocardial infarction (AMI) patients (n= 270, 92.3 +/- 2.3 yr old) with octogenarian AMI patients (n= 2,145, 83.5 +/- 2.7 yr old) enrolled in Korean AMI Registry (KAMIR). Nonagenarians were less likely to have hypertension, diabetes and less likely to be prescribed with beta-blockers, statins, and glycoprotein IIb/IIIa inhibitors compared with octogenarians. Although percutaneous coronary intervention (PCI) was preferred in octogenarians than nonagenarians, the success rate of PCI between the two groups was comparable. In-hospital mortality, the composite of in-hospital adverse outcomes and one year mortality were higher in nonagenarians than in octogenarians. However, the composite of the one year major adverse cardiac events (MACEs) was comparable between the two groups without differences in MI or re-PCI rate. PCI improved 1-yr mortality (adjusted hazard ratio [HR], 0.50; 95% confidence interval [CI], 0.36-0.69, P < 0.001) and MACEs (adjusted HR, 0.47; 95% CI, 0.37-0.61, P < 0.001) without significant complications both in nonagenarians and octogenarians. In conclusion, nonagenarians had similar 1-yr MACEs rates despite of higher in-hospital and 1-yr mortality compared with octogenarian AMI patients. PCI in nonagenarian AMI patients was associated to better 1-yr clinical outcomes.
URI
http://hdl.handle.net/YU.REPOSITORY/32588http://dx.doi.org/10.3346/jkms.2014.29.4.527
ISSN
1011-8934
Appears in Collections:
의과대학 > 내과학교실 > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE