항생제 Fluoroquinolones의 약동학 및 약력학에 관한 최신 정보

Title
항생제 Fluoroquinolones의 약동학 및 약력학에 관한 최신 정보
Other Titles
Current Updates in Pharmacokinetics and Pharmacodynamics of Fluoroquinolones
Author(s)
송필현고영휘
Keywords
Fluoroquinolones; Pharmacokinetics; Pharmacology
Issue Date
201504
Publisher
대한요로생식기감염학회
Citation
Urogenital Tract Infection, v.10, no.1, pp.1 - 6
Abstract
The ultimate goal of antimicrobial treatment is to decrease the morbidity and mortality related to infection. Maximizing these outcomes requires an understanding of the complex interactions between the drug administered, the host, and the infecting pathogen. Pharmacokinetics, which deals with the disposition of a drug in the body, focuses on such parameters as absorption, distribution, and elimination. Pharmacodynamics more specifically focuses on the interaction between the drug concentration at the site of action over time and the resulting antimicrobial effect. Use of quinolones has increased in vitro activity against several important pathogenic organisms as well as augmented pharmacokinetic parameters. These properties result in enhanced pharmacodynamic characteristics and should improve therapeutic outcomes against selected pathogens. In this article the pharmacokinetics and pharmacodynamic potential of these quinolones, particularly fluoroquinolones, is reviewed.
URI
http://hdl.handle.net/YU.REPOSITORY/32574
ISSN
2465-8243
Appears in Collections:
의과대학 > 비뇨기과학교실 > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE