급성허혈뇌졸중 환자의 급성증상발작: 발생률 및예측인자

Title
급성허혈뇌졸중 환자의 급성증상발작: 발생률 및예측인자
Other Titles
Acute Symptomatic Seizures in Patients with Acute Ischemic Stroke: Incidence and Predictive Factors
Author(s)
이세진백현석배성윤
Keywords
Acute symptomatic seizure; Onset seizure; Post-stroke seizure; Acute ischemic stroke; Cerebral infarction
Issue Date
201504
Publisher
대한신경과학회
Citation
대한신경과학회지, v.33, no.2, pp.89 - 96
Abstract
Background: The aim of this study was to establish the incidence, predictive factors, characteristics, and clinical outcomes of acute symptomatic seizures (ASS) after acute ischemic stroke (AIS). Methods: In total, 2,528 consecutive patients with first-ever AIS were included. Patients with a history of epilepsy or provoked seizures due to tumor, head trauma, brain surgery, or high fever were excluded. Onset seizure (OS) and ASS were defined as seizures occurring within 24 hours and 7 days after AIS, respectively. The incidence of ASS, type of seizures, presence of late unprovoked seizure (LUS), MRI, and electroencephalogram were analyzed. Results: ASS and OS occurred in 23 patients (0.9%) and 15 patients (0.6%), respectively; 20 of the patients with ASS (87.0%) had partial seizures and 4 (17.4%) developed status epilepticus. The incidence rates of ASS were 1.3%, 0.3%, and 0.2% in AIS caused by large-artery atherosclerosis, small-vessel occlusion, and cardioembolism, respectively. Of the 23 patients with ASS, the cortex was involved in 19 (82.6%), 16 patients (69.6%) had medium-sized to large lesions, the anterior circulation territory was involved in 21 patients (91.3%), and 4 patients (17.4%) developed MRI-confirmed hemorrhagic transformation of the lesions. Epileptiform discharges were observed in 9 (45%) of the 20 patients with ASS. Three of the 23 patients with ASS (13.0%) developed LUS. Conclusions: The incidence of ASS was 0.9% and was highest in the large-artery atherosclerosis group. The development of ASS was significantly associated with cortical involvement, medium-sized to large lesions, and lesions in the anterior circulation territory. Three of 23 patients (13%) developed LUS.
URI
http://hdl.handle.net/YU.REPOSITORY/32572http://dx.doi.org/10.17340/jkna.2015.2.3
ISSN
1225-7044
Appears in Collections:
의과대학 > 신경과학교실 > Articles
의과대학 > 영상의학과학교실 > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE