Associations of serum 25(OH)D levels with depression and depressed condition in Korean adults: Results from KNHANES 2008-2010

Title
Associations of serum 25(OH)D levels with depression and depressed condition in Korean adults: Results from KNHANES 2008-2010
Author(s)
박경구슬
Issue Date
201404
Citation
Journal of Nutrition and Health, v.47, no.2, pp.113 - 123
Abstract
Purpose: Vitamin D has been known to play an important role in the central nervous system and brain functions in the human body, and cumulative evidence has shown that vitamin D deficiency might be linked with various mental health conditions. Epidemiologic studies have shown that vitamin D deficiency may be associated with higher risk of depression in the US and European populations. However, limited information is available regarding the association between vitamin D status and depression in the Korean population. The objective of this study was to examine the associations between vitamin D levels and prevalence of depression. Methods: We conducted a cross-sectional analysis using nationally representative data from the 2008-2010 Korean National Health and Nutrition Examination Survey from which serum 25-hydroxyvitamin D concentrations were available. A total of 18,735 adults who had available demographic, dietary, and lifestyle information were included in our analysis. We defined depression with a diagnosis by a physician. Depressed condition was defined as having feelings of sadness or depression without diagnosis by a physician. Results: The prev-alence of depression was 1.63% and 5.43% in Korean men and women, respectively; 12.5% of men and 26.1% of women were defined as the group having depressed conditions. In multivariate logistic regression models, no significant associa-tions were observed between vitamin D status and prevalence of depression or depressed conditions in Korean men and women. Conclusion: We found no association between vitamin D insufficiency and depression/depressed condi-tions in Korean adults. Future large prospective studies and randomized controlled trials are needed to confirm this rela-tionship. ? 2014 The Korean Nutrition Society.
URI
http://hdl.handle.net/YU.REPOSITORY/32455http://dx.doi.org/10.4163/jnh.2014.47.2.113
ISSN
2288-3886
Appears in Collections:
생활과학대학 > 식품영양학과 > Articles
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