Prognostic Value of the Age, Creatinine, and Ejection Fraction Score for 1-Year Mortality in 30-Day Survivors Who Underwent Percutaneous Coronary Intervention After Acute Myocardial Infarction

Title
Prognostic Value of the Age, Creatinine, and Ejection Fraction Score for 1-Year Mortality in 30-Day Survivors Who Underwent Percutaneous Coronary Intervention After Acute Myocardial Infarction
Author(s)
김영조Jang Hoon Lee[Jang Hoon Lee]Shung Chull Chae[Shung Chull Chae]Dong Heon Yang[Dong Heon Yang]Hun Sik Park[Hun Sik Park]Yong keun Cho[Yong keun Cho]Chong Jin Kim[Chong Jin Kim]Kee-Sik Kim[Kee-Sik Kim]Seung Ho Hur[Seung Ho Hur]Myung Hwan Bae[Myung Hwan Bae]
Keywords
SYNTAX SCORE; RISK; REGISTRY; PREDICTORS; ANGIOPLASTY; OUTCOMES; EVENTS; TRIAL
Issue Date
201505
Publisher
EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC
Citation
AMERICAN JOURNAL OF CARDIOLOGY, v.115, no.9, pp.1167 - 1173
Abstract
Few simple and effective tools are available for determining the prognosis of 30-day survivors after acute myocardial infarction. We aimed to assess whether the simple age, creatinine, and ejection fraction (ACEF) score could predict 1-year mortality of 12,000 post myocardial infarction 30-day survivors who underwent percutaneous coronary intervention. The ACEF score was computed as follows: (age/ejection fraction) + 1, if the serum creatinine was >2 mg/dl. Accuracy was defined through receiver-operating characteristics analysis and area under the curve (AUC) evaluation. Twelve risk factors were selected and ranked according to their AUC value. Age, ejection fraction, and serum creatinine levels indicated the best AUC value. The ACEF score was significantly higher in the non-survivors (1.95 +/- 0.82 vs 1.28 +/- 0.50; p <0.001) and was an independent predictor of 1-year mortality (adjusted hazard ratio 2.26; p <0.001). The best accuracy was achieved by a prediction model including 12 risk factors (AUC = 0.80), but this did not significantly differ compared with the AUC (0.79) of the ACEF score (p = ns). Adjusted hazard ratios for 1-year mortality were 1 (reference), 3.11 (p <0.001), and 10.38 (p <0.001) for the ACEF(LOW) (ACEF score <1.0), ACEF(MID) (ACEF score 1.0 to 1.39), and ACEF(HIGH) (ACEF score >= 1.4) groups, respectively. The ACEF score may be a novel valid model to stratify the 1-year mortality risk in 30-day survivors who underwent percutaneous coronary intervention after acute myocardial infarction. (C) 2015 Elsevier Inc. All rights reserved.
URI
http://hdl.handle.net/YU.REPOSITORY/32290http://dx.doi.org/10.1016/j.amjcard.2015.02.001
ISSN
0002-9149
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의과대학 > 내과학교실 > Articles
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