The risk factors of early recurrence after hepatectomy in hepatocellular carcinoma

Title
The risk factors of early recurrence after hepatectomy in hepatocellular carcinoma
Author(s)
이동식권순근윤성수김홍진
Keywords
CHRONIC HEPATITIS-B; INTRAHEPATIC RECURRENCE; CURATIVE RESECTION; CLINICAL-FEATURES; PROGNOSIS; CLASSIFICATION; SURVIVAL; OUTCOMES; STAGE
Issue Date
201406
Publisher
KOREAN SURGICAL SOCIETY
Citation
ANNALS OF SURGICAL TREATMENT AND RESEARCH, v.86, no.6, pp.283 - 288
Abstract
Purpose: Early recurrence after hepatectomy is a well-known poor prognostic factor in patients with hepatocellular carcinoma. This study was undertaken to identify the risk factors of early recurrence in patients with hepatocellular carcinoma after hepatectomy. Methods: One hundred and sixty-seven patients that underwent hepatectomy for hepatocellular carcinoma from January 2005 to December 2010 were enrolled. The numbers of patients with or without early recurrence group were 40 and 127, respectively. Clinico-pathologic factors were retrospectively analyzed. Results: Potential risk factors were classified as host, tumor, or surgical factors. Of the host factors examined, lobular hepatitis activity was found to be a significant risk factor of early recurrence, and of the tumor factors, infiltrative type of gross appearance, level of preoperative AFP and worst Edmondson-Steiner grade were significant. Conclusion: The present study shows that an infiltrative gross appearance, a high preoperative AFP level, high lobular hepatitis activity, and a poor Edmondson-Steiner grade are independent risk factors of early recurrence. Accordingly, patients with these risk factors should be followed closely after hepatectomy.
URI
http://hdl.handle.net/YU.REPOSITORY/32048http://dx.doi.org/10.4174/astr.2014.86.6.283
ISSN
2288-6575
Appears in Collections:
의과대학 > 성형외과학교실 > Articles
의과대학 > 영상의학과학교실 > Articles
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