Characteristics of injury of the corticospinal tract and corticoreticular pathway in hemiparetic patients with putaminal hemorrhage

Title
Characteristics of injury of the corticospinal tract and corticoreticular pathway in hemiparetic patients with putaminal hemorrhage
Author(s)
장성호유진선최병연장철훈정영진김성호
Keywords
DIFFUSION TENSOR TRACTOGRAPHY; SPONTANEOUS INTRACEREBRAL HEMORRHAGE; HUMAN BRAIN; STROKE PATIENTS; RECOVERY; LOCATION; INFARCT
Issue Date
201406
Publisher
BIOMED CENTRAL LTD
Citation
BMC NEUROLOGY, v.14
Abstract
Background: No study on the characteristics of injury of the corticospinal tract (CST) or corticoreticular pathway (CRP) in patients with putaminal hemorrhage has been reported. In this study, using diffusion tensor tractography, we attempted to investigate the characteristics of injury of the CST and CRP in hemiparetic patients with putaminal hemorrhage. Method: Fifty seven consecutive patients with putaminal hemorrhage and 57 healthy control subjects were recruited for this study. Diffusion tensor imaging was performed during the early period (8 similar to 30 days) after onset. We defined injury of the CST or CRP in terms of the configuration (discontinuation of a neural tract) or abnormal DTT parameters (the fractional anisotrophy value or fiber number was more than two standard deviations lower than that of normal control subjects). The Motricity Index, the modified Brunnstrom Classification, and the Functional Ambulation Categories were used for evaluation of motor function. Results: Among 57 patients, injury of the CST was found in 41 patients (71.9%) and injury of the CRP was found in 50 patients (87.8%), respectively, and 37 patients (64.9%) had injury of both the CST and CRP. All three motor functions of patients with injury of both the CST and CRP were significantly lower than those of patients with injury of either the CST or CRP (p < 0.05). Conclusion: Our results indicate that the putaminal hemorrhage frequently accompanies injury of both the CST and CRP, and the CRP appears to be more vulnerable to putaminal hemorrhage than the CST. These findings suggest the necessity for evaluation of both the CRP and the CST in patients with putaminal hemorrhage.
URI
http://hdl.handle.net/YU.REPOSITORY/32043http://dx.doi.org/10.1186/1471-2377-14-121
ISSN
1471-2377
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의과대학 > 재활의학교실 > Articles
의과대학 > 신경외과학교실 > Articles
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