Synthesis, Anticancer and Antioxidant Activity of Novel 2,4-Disubstituted Thiazoles

Title
Synthesis, Anticancer and Antioxidant Activity of Novel 2,4-Disubstituted Thiazoles
Author(s)
김정애Tran Nguyen Minh An[Tran Nguyen Minh An]Mungara Anil Kumar[Mungara Anil Kumar]Seung Hyun Chang[Seung Hyun Chang]김미영이갑득[이갑득]
Keywords
ALPHA-AMINOPHOSPHONATES; INHIBITORY-ACTIVITY; DERIVATIVES; AGENTS; DESIGN; POTENT; ANTIBACTERIAL; SERIES
Issue Date
201406
Publisher
WILEY-V C H VERLAG GMBH
Citation
BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.35, no.6, pp.1619 - 1624
Abstract
A new series of carbazole based 2,4-disubstituted thiazole derivatives were synthesized. All the synthesized compounds were tested for their cytotoxicity against three different cancer cell lines A549, MCF-7, and HT29. Some of these compounds showed good cytotoxicity. These compounds were also evaluated for antioxidant activity. Compounds 3a, 3b, 3d-f and 3i showed higher antioxidant activity than standard BHT.
URI
http://hdl.handle.net/YU.REPOSITORY/31988http://dx.doi.org/10.5012/bkcs.2014.35.6.1619
ISSN
0253-2964
Appears in Collections:
약학대학 > 약학부 > Articles
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