Gas-phase self-assembly of soft nanocomposites for efficient gene transfection and photothermal therapy

Title
Gas-phase self-assembly of soft nanocomposites for efficient gene transfection and photothermal therapy
Author(s)
변정훈김영우[김영우]
Keywords
AEROSOL-BASED FABRICATION; IN-SITU SYNTHESIS; GOLD NANOPARTICLES; WATER-PURIFICATION; FILMS; GRAPHENE; NANOSTRUCTURES; FRAGMENTATION; IRRADIATION; GENERATION
Issue Date
201406
Publisher
ROYAL SOC CHEMISTRY
Citation
JOURNAL OF MATERIALS CHEMISTRY B, v.2, no.21, pp.3185 - 3189
Abstract
The gene transfection efficiency of Au@PDMS-PLL soft nanocomposites was higher than those of SiO2-PLL and PEI; and moreover, the nanocomposites did not show significant cell cytotoxicity in in vitro measurements. The soft nanocomposites were also sensitive during photothermal therapy with infrared light, which produced a cytotoxic effect on the targeted HeLa cells.
URI
http://hdl.handle.net/YU.REPOSITORY/31929http://dx.doi.org/10.1039/c4tb00271g
ISSN
2050-750X
Appears in Collections:
공과대학 > 기계공학부 > Articles
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