High-dose vitamin C management in dapsone-induced methemoglobinemia

Title
High-dose vitamin C management in dapsone-induced methemoglobinemia
Author(s)
박신률이경우[이경우]강태신[강태신]
Keywords
ASCORBIC-ACID; TRIAL
Issue Date
201406
Publisher
W B SAUNDERS CO-ELSEVIER INC
Citation
AMERICAN JOURNAL OF EMERGENCY MEDICINE, v.32, no.6
Abstract
Methylene blue is the first-choice treatment of methemoglobinemia, but it is not readily available in most Korean emergency departments because of an import suspension. An 84-year-old woman with dapsone induced massive methemoglobinemia visited our emergency department for unclear mentality and cyanosis. Because methylene blue was not available, we intravenously administrated vitamin C (VC) for symptomatic methemoglobinemia, although VC is not a universally accepted treatment. Vitamin C (10 g intravenously) administered 6 hourly successfully treated the dapsone-induced methemoglobinemia and did not adversely affect renal functions. Thus, we recommend that if methylene blue is unavailable, 6 hourly intravenous administrations of 10 g of VC should be considered for dapsone-induced methemoglobinemia.
URI
http://hdl.handle.net/YU.REPOSITORY/31898http://dx.doi.org/10.1016/j.ajem.2013.11.036
ISSN
0735-6757
Appears in Collections:
의과대학 > 응급의학교실 > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE