Chemical constituents from marine-derived fungus Penicillium glabrum

Title
Chemical constituents from marine-derived fungus Penicillium glabrum
Author(s)
심상희박소연민진영
Keywords
3 methyldesmethoxyyangonin; chemical compound; ergosterol; hydroxysulochrin; questin; questinol; sulochrin; unclassified drug; article; chemical composition; chemical structure; drug isolation; extraction and extracts; marine biology; Penicillium glabrum; spectroscopy
Issue Date
201406
Citation
Korean Journal of Pharmacognosy, v.45, no.2, pp.101 - 106
Abstract
Marine-derived microbes have yielded a variety of metabolites so far. In the course of the project to find metabolites from marine microbes, an isolate of Penicillium glabrum (SF 5317) was selected for chemical investigation. A large scale culture of this strain in PDA media was extracted with an organic solvent and the extract was subjected to a serious of chromatography, which led to six metabolites. Their chemical structures were elucidated as sulochrin (1), questin (2), questinol (3), ergosterol (4), 3-methyldesmethoxyyangonin (5), and hydroxysulochrin (6) on the basis of spectroscopic data. To the best of our knowledge, this is the second isolation of compounds 5 and 6 in nature and especially 6 is isolated from Penicillium sp. for the first time.
URI
http://hdl.handle.net/YU.REPOSITORY/31870
ISSN
0253-3073
Appears in Collections:
생명공학부 > 생명공학부 > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE