Anaphylaxis to topical bovine thrombin used for hemostasis during surgery for herniated nucleus pulposus −A case report−

Title
Anaphylaxis to topical bovine thrombin used for hemostasis during surgery for herniated nucleus pulposus −A case report−
Author(s)
이덕희김혁구[김혁구]이혜미한지수[한지수]
Keywords
Anaphylaxis; Epinephrine; Topical bovine thrombin.
Issue Date
201507
Publisher
대한마취통증의학회
Citation
Anesthesia and Pain Medicine, v.10, no.3, pp.187 - 191
Abstract
Anaphylaxis is a type I allergic reaction and its clinical features occur after re-exposure to the same allergen. Numerous types of drugs can cause anaphylaxis during general anesthesia. Topical bovine thrombin (TBT) is usually used for hemostasis during surgery. However, TBT can cause interruption of the normal blood coagulation pathways, delay wound repair, and lead to uncontrolled bleeding, anaphylaxis, or death. Anaphylaxis caused by TBT during the perioperative period is very rare. We report the case of a patient who developed severe hypotension, tachycardia, and bronchospasm while undergoing discectomy for herniated nucleus pulposus. Based on the symptoms and signs, anaphylaxis was considered most likely. Identification of the causative agents is important in these cases because it can be very helpful for the management and prevention of anaphylaxis.
URI
http://hdl.handle.net/YU.REPOSITORY/31490
ISSN
1975-5171
Appears in Collections:
의과대학 > 마취통증의학교실 > Articles
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