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dc.contributor.author심상희ko
dc.contributor.author이위ko
dc.contributor.authorWei Zhou[Wei Zhou]ko
dc.contributor.author이동성[이동성]ko
dc.contributor.author김윤철[김윤철]ko
dc.contributor.author김영호[김영호]ko
dc.date.accessioned2015-12-17T04:08:10Z-
dc.date.available2015-12-17T04:08:10Z-
dc.date.created2015-11-13-
dc.date.issued201407-
dc.identifier.citationTETRAHEDRON LETTERS, v.55, no.30, pp.4086 - 4090-
dc.identifier.issn0040-4039-
dc.identifier.urihttp://hdl.handle.net/YU.REPOSITORY/31421-
dc.identifier.urihttp://dx.doi.org/10.1016/j.tetlet.2014.05.117-
dc.description.abstractA novel ergosterol conjunction-type alkaloid, hericirine (1), was isolated from the dried fruiting bodies of Hericium erinaceum. The overall framework of 1 was isolated, and combined with hericerin and ergosterol. Its structure was elucidated based on spectroscopic analysis using 1D and 2D NMR, IR and HRESIMS techniques. We found that hericirine significantly inhibited protein expression of iNOS and COX-2 and reduced NO, PGE(2), TNE-alpha, IL-6 and IL-1 beta production in RAW264.7 cells exposed to LPS. (C) 2014 Elsevier Ltd. All rights reserved.-
dc.language영어-
dc.publisherPERGAMON-ELSEVIER SCIENCE LTD-
dc.subjectAROMATIC-COMPOUNDS-
dc.subjectMUSHROOM-
dc.subjectMACROPHAGES-
dc.titleHericirine, a novel anti-inflammatory alkaloid from Hericium erinaceum-
dc.typeArticle-
dc.identifier.wosid000339128700012-
dc.identifier.scopusid2-s2.0-84904040677-
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