Revascularization for patients with idiopathic thrombocytopenic purpura and coronary artery disease

Title
Revascularization for patients with idiopathic thrombocytopenic purpura and coronary artery disease
Author(s)
Kim, U[Kim, Ung]Lee, CH[Lee, Chan-Hee]
Keywords
ACUTE MYOCARDIAL-INFARCTION; INTRAVENOUS IMMUNOGLOBULIN; STEROID-THERAPY
Issue Date
201407
Citation
Korean Circulation Journal, v.44, no.4, pp.264 - 267
Abstract
Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disorder with a low platelet count characterized by premature platelet destruction and suppression of platelet production mediated by autoantibodies, which may predispose to bleeding. Although the prevalence of coronary artery disease (CAD) in ITP seems to be rare, their co-occurrence is not unusual. Patients with ITP have increased risks for thrombosis and atherosclerosis associated with hemostatic factors, endothelial damage, and the negative effects of steroid and immunoglobulin therapies. Thus, the coexistence of ITP and CAD presents complex problems requiring a balance between hemorrhagic risk and prevention of thrombosis. Here, the authors present two patients with ITP, who were revascularized in different ways for CAD. Although the optimal management of thrombocytopenic patients with CAD is uncertain, individualized treatment modalities can be useful in patients with ITP and CAD. Copyright ? 2014 The Korean Society of Cardiology.
URI
http://hdl.handle.net/YU.REPOSITORY/31396http://dx.doi.org/10.4070/kcj.2014.44.4.264
ISSN
1738-5520
Appears in Collections:
중앙도서관 > rims journal
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