The different maturation of the corticospinal tract and corticoreticular pathway in normal brain development: diffusion tensor imaging study

Title
The different maturation of the corticospinal tract and corticoreticular pathway in normal brain development: diffusion tensor imaging study
Author(s)
손수민장성호여상석[여상석]
Keywords
CHRONIC STROKE PATIENTS; MAGNETIC-RESONANCE; PROXIMAL WEAKNESS; MOTOR FUNCTION; WHITE-MATTER; TRACTOGRAPHY; INJURY; STIMULATION; CHILDHOOD; CHILDREN
Issue Date
201408
Publisher
FRONTIERS RESEARCH FOUNDATION
Citation
FRONTIERS IN HUMAN NEUROSCIENCE, v.8
Abstract
Background and Purpose: The corticospinal tract (CST) and corticoreticular pathway (CRP) are known to be important neural tracts for motor development. However, little is known about the difference in maturation of the CST and CRP In this study, using diffusion tensor imaging (DTI), we investigated maturation of the CST and CRP in typically developed children and normal healthy adults. Methods: We recruited 75 normal healthy subjects for this study. DTI was performed using 1.5-T, and the CST and CRP were reconstructed using DTI-Studio software. Values of fractional anisotropy (FA) and fiber volume (FV) of the CST and CRP were measured. Results: In the current study, the threshold points for CST and CRP maturation were different in normal brain development. Change in FA value of the CST showed a steep increase until 7 years of age and then a gradual increase until adulthood, however, the CRP showed a steep increase only until 2 years of age and then a very gradual increase or plateau until adulthood. In terms of FV, the CST showed a steep increase until 12 years and then a gradual increase until adulthood, in contrast, the CRP showed gradual increase of FV across whole age range (0-25 years). Conclusion: The difference in maturation process between CST and CRP appears to be related to different periods of fine and gross motor development. This radiologic information can provide a scientific basis for understanding development in motor function.
URI
http://hdl.handle.net/YU.REPOSITORY/31286http://dx.doi.org/10.3389/fnhum.2014.00573
ISSN
1662-5161
Appears in Collections:
의과대학 > 재활의학교실 > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE