Regioselective synthesis of novel and diverse naphtho[1,2-b]furan-3-carboxamides and benzofuran-3-carboxamides by cascade formal [3+2] cycloaddition

Title
Regioselective synthesis of novel and diverse naphtho[1,2-b]furan-3-carboxamides and benzofuran-3-carboxamides by cascade formal [3+2] cycloaddition
Author(s)
이용록하립개
Keywords
CATALYZED INTRAMOLECULAR CYCLIZATION; CHIRAL NAPHTHOQUINONES; EFFICIENT SYNTHESIS; ACTIVATED QUINONES; BETA-KETOESTERS; O-ARYLATION; BENZOFURANS; DERIVATIVES; 1,4-NAPHTHOQUINONES; CHEMISTRY
Issue Date
201408
Publisher
ROYAL SOC CHEMISTRY
Citation
RSC ADVANCES, v.4, no.69, pp.36905 - 36916
Abstract
A novel and efficient In(OTf)(3)-catalyzed cascade formal [3 + 2] cycloaddition of 1,4-naphthoquinones or benzoquinones with beta-ketoamides was developed to provide naphtho[1,2-b]furan-3-carboxamides and benzofuran-3-carboxamides. This methodology has broad substrate scope that can afford novel and diverse naphtho[1,2-b]furan-3-carboxamides and benzofuran-3-carboxamides with high regioselectivity in good to excellent yields. Furthermore, this methodology is expected to be applicable to the synthesis of biologically-active complex molecules bearing naphtho[1,2-b] furan-3-carboxamides and benzofuran-3-carboxbenzamides.
URI
http://hdl.handle.net/YU.REPOSITORY/31176http://dx.doi.org/10.1039/c4ra07862d
ISSN
2046-2069
Appears in Collections:
공과대학 > 화학공학부 > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE