Detection of exonic variants within the melanocortin 1 receptor (MC1R) gene in Black Silky, White Leghorn and Golden duckwing Araucana chicken

Title
Detection of exonic variants within the melanocortin 1 receptor (MC1R) gene in Black Silky, White Leghorn and Golden duckwing Araucana chicken
Author(s)
여정수이윤석[이윤석]형기은하재정[하재정]이준구[이준구]김병기[김병기]오동엽[오동엽]
Keywords
PLUMAGE COLOR; PIGMENTATION; 1-RECEPTOR; EXTENSION; MUTATIONS; RECEPTOR
Issue Date
201408
Publisher
SPRINGER
Citation
MOLECULAR BIOLOGY REPORTS, v.41, no.8, pp.4843 - 4846
Abstract
The melanocortin 1 receptor (MC1R) gene can be considered a candidate functional gene for the pigmentation of plumage color. The aim of this study was to investigate the association between the genotype frequencies of g.69 T > C, g.376 G > A and g.427 A > G SNPs within the MC1R gene in Black silky (O), Golden duckwing Araucana (GA) and White Leghorn (W). The CC and AA genotype frequencies of g.69 T > C and g.427 A > G SNPs in White Leghorn (W) were both 1.000, and the TT genotype frequency of the g.69 T > C SNP in Golden duckwing Araucana (GA) was also 1.000. The GG and AA genotype frequencies of g.376 G > A and g.427 A > G SNPs in Black silky (O) were both 0.100. When a haplotype is observed using a combination of markers, a Golden duckwing Araucana (GA) can especially be distinguished when it is a TAG, TGG and TAA type in the SNP combination of the MC1R gene. In case of the CAA types, only White Leghorn (W) could specifically be distinguished. Therefore, three SNPs in MC1R may provide identification in chicken breeds.
URI
http://hdl.handle.net/YU.REPOSITORY/31163http://dx.doi.org/10.1007/s11033-014-3394-0
ISSN
0301-4851
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생명공학부 > 생명공학부 > Articles
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