Eco-friendly synthesis of diverse and valuable 2-pyridones by catalyst- and solvent-free thermal multicomponent domino reaction

Title
Eco-friendly synthesis of diverse and valuable 2-pyridones by catalyst- and solvent-free thermal multicomponent domino reaction
Author(s)
이용록테즈나라얀포우델김성홍[김성홍]
Keywords
BIOLOGICAL EVALUATION; FUSARIUM-OXYSPORUM; ORGANIC-REACTIONS; IN-VIVO; INHIBITORS; DERIVATIVES; PYRIDONES; DESIGN; CYCLOADDITION; KINASE
Issue Date
201509
Publisher
ROYAL SOC CHEMISTRY
Citation
GREEN CHEMISTRY, v.17, no.9, pp.4579 - 4586
Abstract
An efficient and highly eco-friendly synthesis of diverse and functionalized 2-pyridone derivatives in good yield via the thermal multicomponent reaction of 4-oxo-4H-chromene-3-carbaldehydes with 1,3-diketoesters and anilines or primary aliphatic amines under catalyst-and solvent-free conditions is described. This reaction proceeds via domino Knoevenagel condensation/Michael addition/ring opening/ring closure reactions.
URI
http://hdl.handle.net/YU.REPOSITORY/31008http://dx.doi.org/10.1039/c5gc01526j
ISSN
1463-9262
Appears in Collections:
공과대학 > 화학공학부 > Articles
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