Epidemiological Aspects of Pertussis among Adults and Adolescents in a Korean Outpatient Setting: A Multicenter, PCR-Based Study

Title
Epidemiological Aspects of Pertussis among Adults and Adolescents in a Korean Outpatient Setting: A Multicenter, PCR-Based Study
Author(s)
신경철박성훈[박성훈]이선화[이선화]시기현[시기현]박용범[박용범]이명구[이명구]유광하[유광하]김휘정[김휘정]박재석[박재석]조재화[조재화]고용천[고용천]이수걸[이수걸]천기태[천기태]김도일[김도일]하전욱[하전욱]이재명[이재명]서지원[서지원]정의훈[정의훈]정기석[정기석]
Keywords
POLYMERASE-CHAIN-REACTION; BORDETELLA-PERTUSSIS; INFECTION; RESURGENCE; COUGH; VACCINATION; DIPHTHERIA; DIAGNOSIS; CHILDREN; TETANUS
Issue Date
201409
Publisher
KOREAN ACAD MEDICAL SCIENCES
Citation
JOURNAL OF KOREAN MEDICAL SCIENCE, v.29, no.9, pp.1232 - 1239
Abstract
Epidemiological data of Bordetella pertussis infection among adolescents and adults are limited in Korea. Patients (>= 11 yr of age) with a bothersome cough for less than 30 days were enrolled during a 1-yr period at 22 hospitals in Korea. Nasopharyngeal swabs were collected for polymerase chain reaction (PCR) and for bacteriologic culture. In total, 490 patients were finally enrolled, and 34 (6.9%) patients tested positive for B. pertussis; cough duration (14.0 days [7.0-21.0 days]) and age distribution were diverse. The incidence was the highest in secondary referral hospitals, compared to primary care clinics or tertiary referral hospitals (24/226 [10.6%] vs. 3/88 [3.4%] vs. 7/176 [4.0%], P = 0.012), and the peak incidence was observed in February and August (15.8% and 15.9%), with no confirmed cases between March and June. In the multivariate analysis, post-tussive vomiting was significantly associated with pertussis (odds ratio, 2.508; 95% confidence interval, 1.146-5.486) and secondary referral hospital showed a borderline significance. In conclusion, using a PCR-based method, 6.9% of adolescent and adult patients with an acute cough illness had pertussis infection in an outpatient setting. However, hospital levels and seasonal trends must be taken into account to develop a better strategy for controlling pertussis.
URI
http://hdl.handle.net/YU.REPOSITORY/30801http://dx.doi.org/10.3346/jkms.2014.29.9.1232
ISSN
1011-8934
Appears in Collections:
의과대학 > 내과학교실 > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE