Alternaria alternata 피부 감염 1예

Title
Alternaria alternata 피부 감염 1예
Other Titles
A Case of Cutaneous Infection by Alternaria alternata
Author(s)
송승현김연웅김병수최진화신동훈최종수
Keywords
Alternaria alternata; Cutaneous alternariosis; Ketoconazole
Issue Date
201409
Publisher
대한의진균학회
Citation
대한의진균학회지, v.19, no.3, pp.76 - 81
Abstract
Alternaria(A.) species are common saprophyte found in the environment such as soil, air, and plants. They are not usually pathogenic in humans but recently, infections by these fungi have occasionally beenreported, occurring mostly in immunocompromised patients. They can cause hypersensitivity pneumonitis,bronchial asthma, or allergic rhinitis and rarely skin infection. A 76-year-old man presented with multipleerythematous papules, plaque and pustules with purpuric patches on both forearms and dorsal hands for6 months. He had been treated for Parkinson's disease and dementia for 3 years but had not been takingany immunosuppressants. Direct smear with KOH was negative. Histopatholoigically, neutrophilicabscess, suppurative granulomatous inflammation and round spores were observed in the dermis. Periodicacid-Schiff and Methenamine silver stains revealed round to oval shaped spores. The biopsy specimenwas cultured in potato dextrose agar and a cottony olive green to gray colored colony with black to brownreverse grew at 7 days of culture. The slide culture stained with lactophenol-cotton blue showed brownseptated hyphae and obclavate conidia with brown muriform septation. The nucleotide sequences of theribosomal internal transcribed spacer region of cultured colonies and paraffin blocks of biopsy specimenwere identical to that of A. alternata. He was treated with topical ketoconazole cream application for 4months, and healed leaving hyperpigmentation with scales.
URI
http://hdl.handle.net/YU.REPOSITORY/30741
ISSN
1226-4709
Appears in Collections:
의과대학 > 영상의학과학교실 > Articles
의과대학 > 피부과학교실 > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE