Preparation of Au and Ag nanoparticles using Artemisia annua and their in vitro antibacterial and tyrosinase inhibitory activities

Title
Preparation of Au and Ag nanoparticles using Artemisia annua and their in vitro antibacterial and tyrosinase inhibitory activities
Author(s)
이용록바사베나가라즈아크베르이드하야둘라
Keywords
PLASMON RESONANCE SCATTERING; SILVER NANOPARTICLES; GOLD NANOPARTICLES; EXTRACELLULAR SYNTHESIS; BACTERICIDAL ACTIVITY; GREEN SYNTHESIS; BIOSYNTHESIS; PARTICLES; EXTRACT; NANOTECHNOLOGY
Issue Date
201410
Publisher
ELSEVIER SCIENCE BV
Citation
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, v.43, pp.58 - 64
Abstract
This work describes a plant-mediated approach to the preparation of metal nanoparticles using leaf extract of Artemisia annua (A. annua), an ethno-medicinal plant widely found in Asia, which was used as reducing and stabilizing agent. A. annua is used in traditional Chinese medicine to alleviate fever. Au and Ag nanoparticles were prepared using a one-step aqueous method at room temperature without any toxic chemicals. The formation of Au and Ag nanoparticles was monitored by UV-vis spectroscopy. Synthesized nanoparticles were characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), energy dispersive X-ray analysis (EDX), Fourier transform infrared (FT-IR) spectroscopy, and thermogravimetric analysis (TGA). TEM analysis of Au nanoparticles showed that they had triangular and spherical shapes with sizes ranging from 15 to 40 nm. The silver nanoparticles were predominantly spherical and uniformly sized (30-50 nm). The Au and Ag nanoparticles produced showed significant tyrosinase inhibitory and antibacterial effects. These results suggest that the synthesized nanoparticles provide good alternatives in varied medical and industrial applications. (C) 2014 Elsevier B.V. All rights reserved.
URI
http://hdl.handle.net/YU.REPOSITORY/30624http://dx.doi.org/10.1016/j.msec.2014.06.043
ISSN
0928-4931
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공과대학 > 화학공학부 > Articles
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