Effectiveness of sodium picosulfate/magnesium citrate (PICO) for colonoscopy preparation

Title
Effectiveness of sodium picosulfate/magnesium citrate (PICO) for colonoscopy preparation
Author(s)
김재황송기환[송기환]서우석[서우석]정진식[정진식]김동식[김동식]김상우[김상우]곽동민[곽동민]황종성[황종성]김현진[김현진]박만우[박만우]
Keywords
macrogol; picosulfate sodium; abdominal cramp; abdominal pain; adult; aged; Article; bloating; colonoscopy; comparative effectiveness; controlled study; diet restriction; double blind procedure; drug efficacy; female; health care quality; health survey; human; insomnia; intestine preparation; major clinical study; male; named inventories, questionnaires and rating scales; nausea; patient preference; patient satisfaction; preoperative care; questionnaire; randomized controlled trial; secondary care center
Issue Date
201410
Citation
Annals of Coloproctology, v.30, no.5, pp.222 - 227
Abstract
Purpose: Bowel preparation with sodium phosphate was recently prohibited by the U.S. Food and Drug Administration. Polyethylene glycol (PEG) is safe and effective; however, it is difficult to drink. To identify an easy bowel preparation method for colonoscopy, we evaluated three different bowel preparation regimens regarding their efficacy and patient satisfaction. Methods: In this randomized, comparative study, 892 patients who visited a secondary referral hospital for a colonoscopy between November 2012 and February 2013 were enrolled. Three regimens were evaluated: three packets of sodium picosulfate/magnesium citrate (PICO, group A), two packets of PICO with 1 L of PEG (PICO + PEG 1 L, group B), and two packets of PICO with 2 L of PEG (PICO + PEG 2 L, group C). A questionnaire survey regarding the patients' preference for the bowel preparation regimen and satisfaction was conducted before the colonoscopies. The quality of bowel cleansing was scored by the colonoscopists who used the Aronchick scoring scale and the Ottawa scale. Results: The patients' satisfaction rate regarding the regimens were 72% in group A, 64% in group B, and 45.9% in group C. Nausea and abdominal bloating caused by the regimens were more frequent in group C than in group A or group B (P < 0.01). Group C showed the lowest preference rate compared to the other groups (P < 0.01). Group C showed better right colon cleansing efficacy than group A or group B. Conclusion: Group A exhibited a better result than group B or group C in patient satisfaction and preference. In the cleansing quality, no difference was noted between groups A and C. ? 2014 The Korean Society of Coloproctology.
URI
http://hdl.handle.net/YU.REPOSITORY/30584http://dx.doi.org/10.3393/ac.2014.30.5.222
ISSN
2287-9714
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의과대학 > 성형외과학교실 > Articles
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