Internet-based Control Recruitment for a Case-Control Study of Major Risk Factors for Stroke in Korea: Lessons from the Experience

Title
Internet-based Control Recruitment for a Case-Control Study of Major Risk Factors for Stroke in Korea: Lessons from the Experience
Author(s)
이준Jong-Moo Park[Jong-Moo Park]Yong-Jin Cho[Yong-Jin Cho]Kyung Bok Lee[Kyung Bok Lee]Tai Hwan Park[Tai Hwan Park]Soo Joo Lee[Soo Joo Lee]Moo-Ku Han[Moo-Ku Han]Youngchai Ko[Youngchai Ko]Jae-Kwan Cha[Jae-Kwan Cha]Hee-Joon Bae[Hee-Joon Bae]
Keywords
ISCHEMIC-STROKE; CASE-FATALITY
Issue Date
201411
Publisher
ELSEVIER SCIENCE BV
Citation
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, v.23, no.10, pp.2559 - 2565
Abstract
This study aimed to estimate the population-attributable risks (PARs) of 9 major risk factors for stroke in Korea through a case-control study and to test the feasibility and validity of internet-based control recruitment. Methods: From April 2008 to September 2009, controls were enrolled via internet after providing consent for participation through a web-based survey. The cases included patients who were admitted to the participating centers due to acute stroke or transient ischemic attack within 7 days of onset during the study period. Each control was age- and sex-matched with 2 cases. Adjusted odd ratios, age-standardized prevalence, and PARs were estimated for the 9 major risk factors using the prevalence of risk factors in the control group and the age and sex characteristics from Korea's national census data. Results: In total, 1041 controls were matched to 2082 stroke cases. Because of a shortage of elderly controls in the internet-based recruitment, 248 controls were recruited off-line. The PARs were 23.44%, 10.95%, 51.32%, and 6.35% for hypertension, diabetes, smoking, and stroke history, respectively. Hypercholesterolemia, atrial fibrillation, obesity, coronary heart disease, and a family history of stroke were not associated with stroke. Comparison with education and religion of the control group with that mentioned in the national census data showed a notable difference. Conclusions: The study results imply that internet-based control recruitment for a case-control study requires careful selection of risk factors with high self-awareness and effective strategies to facilitate the recruitment of elderly participants.
URI
http://hdl.handle.net/YU.REPOSITORY/30468http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2014.05.026
ISSN
1052-3057
Appears in Collections:
의과대학 > 신경과학교실 > Articles
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