Gastrointestinal stromal tumors (GISTs) of the stomach: a multicenter, retrospective study of curatively resected gastric GISTs

Title
Gastrointestinal stromal tumors (GISTs) of the stomach: a multicenter, retrospective study of curatively resected gastric GISTs
Author(s)
김세원채현동[채현동]김인환[김인환]김인호[김인호]곽상규[곽상규]
Keywords
LONG-TERM; LAPAROSCOPIC SURGERY; SURVIVAL; ERA; MANAGEMENT; DIAGNOSIS; MESYLATE
Issue Date
201412
Publisher
KOREAN SURGICAL SOCIETY
Citation
ANNALS OF SURGICAL TREATMENT AND RESEARCH, v.87, no.6, pp.298 - 303
Abstract
Purpose: The standard treatment for primary localized gastric gastrointestinal stromal tumor (GIST) is surgical resection. The clinical behavior of gastric GIST after surgical resection is extremely variable. We conducted a multicenter, retrospective study of gastric GISTs patients who underwent curative surgical resection to evaluate clinical features and the prognosis of surgically treated gastric GISTs. Methods: We performed a retrospective study on 406 consecutive patients who underwent curative resections for localized gastric GIST at four university hospitals in Daegu, Korea, between March 1998 and March 2012. The retrospectively collected medical records were reviewed with respect to clinical parameters including age, gender, tumor location, surgical approach, and recurrence. Results: There were 406 patients: 157 males (38.7%) and 249 females (61.3%), with a mean age of 60.8 +/- 10.8 (standard deviation) years. The mean tumor size was 4.9 cm (range, 0.3-29 cm). Curative surgical resection was performed in all patients without tumor rupture or spillage. Laparoscopic wedge resections were performed in 156 patients (38.4%) and open resections in 250 patients (61.6%). The tumor size of the laparoscopic wedge resection group was smaller than that of open resection group (3.45 cm vs. 5.46 cm; P < 0.001). There were 11 recurrent cases (2.7%). No recurrence was observed in patients who underwent laparoscopic wedge resections. Conclusion: Gastric GISTs had a low recurrence rate after curative resection in our series. Laparoscopic gastric wedge resection is feasible for treating gastric GISTs in selected patients.
URI
http://hdl.handle.net/YU.REPOSITORY/30352http://dx.doi.org/10.4174/astr.2014.87.6.298
ISSN
2288-6575
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의과대학 > 성형외과학교실 > Articles
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