Clinical chemistry values in elderly Korean people: single institutional study

Title
Clinical chemistry values in elderly Korean people: single institutional study
Author(s)
김유경서보영[서보영]함지연[함지연]송정흡[송정흡]송경은[송경은]
Keywords
HEALTHY
Issue Date
201306
Publisher
KOREAN MEDICAL ASSOC
Citation
JOURNAL OF THE KOREAN MEDICAL ASSOCIATION, v.56, no.6, pp.533 - 539
Abstract
Laboratory values change with age and interpreting laboratory results from elderly people using the reference intervals for younger adults may not be appropriate. The authors investigated the distribution patterns of routine chemistry values from elderly people to determine whether current reference intervals are also valid for elderly people. A total of 1,215 persons older than 65 years and 1,827 healthy adults below 65 years of age were evaluated. Blood samples were collected after an overnight fast and analyzed for chemistry tests. Computing the central 95th percentile showed that the total protein, albumin, ALP, LD, creatinine, uric acid, triglyceride, HDL-cholesterol, and electrolytes of elderly people were within the standard reference intervals used in our laboratory. For AST and ALT, the upper range of the central 95th percentile in the elderly population was found to be outside the common reference interval. However, the central 90th percentile values of AST and ALT were compatible with the common reference intervals. GOT, BUN, total cholesterol, LDL-cholesterol, and glucose showed higher values than the upper limits of the reference intervals. For common clinical chemistry tests, the common reference values in general should be applicable to elderly people, even though some parameters showed wider distributions in the elderly.
URI
http://hdl.handle.net/YU.REPOSITORY/29869http://dx.doi.org/10.5124/jkma.2013.56.6.533
ISSN
1975-8456
Appears in Collections:
의과대학 > 진단검사의학교실 > Articles
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