Isolation and structure determination of metabolites from cultures of aspergillus protuberus

Title
Isolation and structure determination of metabolites from cultures of aspergillus protuberus
Author(s)
백소윤심상희
Issue Date
201306
Citation
Korean Journal of Microbiology, v.49, no.2, pp.179 - 183
Abstract
Marine-derived microbes have yielded a variety of metabolites so far. In the course of the project to find metabolites from marine microbes, an isolate of Aspergillus protuberus (SF 5767) was selected for chemical investigation. A large scale culture of this strain in PDA media was extracted with an organic solvent and the extract was fractionated by silica gel column chromatography. Repeated reverse phase HPLC of the fractions led to the isolation of three metabolites. Their chemical structures were elucidated as deoxybrevianamide E (1), brevianamide V (2), and ergosterol peroxide (3) on the basis of spectroscopic data including MS, NMR, and UV. To the best of our knowledge, chemical investigation of A. protuberus was conducted for the first time in this study. ? 2013, The Microbiological Society of Korea.
URI
http://hdl.handle.net/YU.REPOSITORY/29790http://dx.doi.org/10.7845/kjm.2013.3026
ISSN
0440-2413
Appears in Collections:
중앙도서관 > rims journal
생명공학부 > 생명공학부 > Articles
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