Elucidation of Antifungal Metabolites Produced by Pseudomonas aurantiaca IB5-10 with Broad-Spectrum Antifungal Activity

Title
Elucidation of Antifungal Metabolites Produced by Pseudomonas aurantiaca IB5-10 with Broad-Spectrum Antifungal Activity
Author(s)
심상희박귀교[박귀교]임종희김상달
Keywords
PHENAZINE-1-CARBOXYLIC ACID; CHLORORAPHIS GP72; 2-HYDROXYPHENAZINE
Issue Date
201203
Publisher
KOREAN SOC MICROBIOLOGY & BIOTECHNOLOGY
Citation
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.22, no.3, pp.326 - 330
Abstract
Antifungal metabolites were isolated from a culture of Pseudomonas aurantiaca IBS-10. Chemical structures of the metabolites were elucidated as phenazine-1-carboxylic acid (PCA; 1), 2-hydroxyphenazine (2-OH-PHZ; 2), and cyclo-(L-Pro-L-Val; 3), respectively, based on spectroscopic methods. Among them, 3 was isolated for the first time from this strain. The antifungal activities of 1-3 were evaluated against a variety of plant pathogens. To the best of our knowledge, the antifungal activities of 3 against plant fungal pathogens have been evaluated for the first time in this work. PCA (1) showed the most potent antifungal activities against Phytophthora capsici, Rhizoctonia solani AG-1(IA), and Pythium ultimum with MICs (mu g-ml) of less than 1.0, 1.3, and 2.0, respectively. On the other hand, 2-OH-PHZ (2) showed potent antifungal activity against R. solani AG-1(IA) with the MIC (mu g/ml) of 2.0, whereas it showed moderate antifungal activity against P. ultimum with the MIC (mu g/ml) of 50.0. In addition, 3 showed antifungal activity against only R. solani AG-1(IA).
URI
http://hdl.handle.net/YU.REPOSITORY/29665http://dx.doi.org/10.4014/jmb.1106.06042
ISSN
1017-7825
Appears in Collections:
생명공학부 > 생명공학부 > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE