Motor recovery mechanism in a quadriplegic patient with locked-in syndrome

Title
Motor recovery mechanism in a quadriplegic patient with locked-in syndrome
Author(s)
장성호권혁규
Keywords
DIFFUSION TENSOR TRACTOGRAPHY; CORONA RADIATA INFARCT; CORTICOSPINAL TRACT; PONTINE INFARCT; PERIINFARCT REORGANIZATION; INTRACEREBRAL HEMORRHAGE; HEMIPARETIC PATIENTS; BRAIN; AREA
Issue Date
201203
Publisher
IOS PRESS
Citation
NEUROREHABILITATION, v.30, no.2, pp.113 - 117
Abstract
Locked-in syndrome (LIS) is a rare neurologic condition caused by bilateral pontine lesions. Quadriplegia is one of the most serious clinical manifestations in patients with LIS. However, little is known about the motor recovery mechanism of quadriplegia in patients with LIS. In the current study, we present with a quadriplegic patient with bilateral pontine infarcts, whose motor function appeared to be reorganized into the peri-infarct areas of the infarcted pons, as demonstrated by diffusion tensor tractography (DTT). A 60-year-old was diagnosed as LIS due to bilateral pontine infarcts 6 years ago. The patient presented with complete paralysis of all four extremities at onset. After slow motor recovery, the patient was able to move all joint muscles against gravity and demonstrated some fine motor activity at the time of DTT scanning (6 years after onset). Results of DTTs for the corticospinal tract (CST) in both hemispheres showed that the CSTs originated from the primary motor cortex, descended along the known CST pathway, and passed through lateral areas of infarcts in the pons. Therefore, motor function of the four extremities of this patient appears to have been recovered by the CST, which passed through the lateral areas to the pontine infarcts.
URI
http://hdl.handle.net/YU.REPOSITORY/29618http://dx.doi.org/10.3233/NRE-2012-0734
ISSN
1053-8135
Appears in Collections:
의과대학 > 재활의학교실 > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE