Chronic Obstructive Pulmonary Disease Assessment Test Can Predict Depression: A Prospective Multi-Center Study

Title
Chronic Obstructive Pulmonary Disease Assessment Test Can Predict Depression: A Prospective Multi-Center Study
Author(s)
이관호이영석[이영석]박성훈[박성훈]이도성[이도성]박성우[박성우]김영삼[김영삼]라성원[라성원]정기석[정기석]박영범[박영범]황영일[황영일]
Keywords
PATIENT HEALTH QUESTIONNAIRE-9; QUALITY-OF-LIFE; COPD PATIENTS; ACUTE EXACERBATIONS; CARE; SYMPTOMS; ANXIETY; REHABILITATION; POPULATION; VALIDATION
Issue Date
201307
Publisher
KOREAN ACAD MEDICAL SCIENCES
Citation
JOURNAL OF KOREAN MEDICAL SCIENCE, v.28, no.7, pp.1048 - 1054
Abstract
This study was conducted to investigate the association between the chronic obstructive pulmonary disease (COPD) assessment test (CAT) and depression in COPD patients. The Korean versions of the CAT and patient health questionnaire-9 (PHQ-9) were used to assess COPD symptoms and depressive disorder, respectively. In total, 803 patients with COPD were enrolled from 32 hospitals and the prevalence of depression was 23.8%. The CAT score correlated well with the PHQ-9 score (r=0.631; P<0.001) and was significantly associated with the presence of depression (beta +/- standard error, 0.452 +/- 0.020; P<0.001). There was a tendency toward increasing severity of depression in patients with higher CAT scores. By assessment groups based on the 2011 Global Initiative for Chronic Obstructive Lung Disease guidelines, the prevalence of depression was affected more by current symptoms than by airway limitation. The area under the receiver operating characteristic curve for the CAT was 0.849 for predicting depression, and CAT scores >= 21 had the highest accuracy rate (80.6%). Among the eight CAT items, energy score showed the best correlation and highest power of discrimination. CAT scores are significantly associated with the presence of depression and have good performance for predicting depression in COPD patients.
URI
http://hdl.handle.net/YU.REPOSITORY/29330http://dx.doi.org/10.3346/jkms.2013.28.7.1048
ISSN
1011-8934
Appears in Collections:
의과대학 > 내과학교실 > Articles
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