Risk Factors between Patients with Lone and Non-Lone Atrial Fibrillation

Title
Risk Factors between Patients with Lone and Non-Lone Atrial Fibrillation
Author(s)
신동구이성호[이성호]박성준[박성준]변경민[변경민]온영균[온영균]김준수[김준수]조정관[조정관]김윤년[김윤년]김영훈[김영훈]
Keywords
ALCOHOL-CONSUMPTION; FOLLOW-UP; FAMILIAL AGGREGATION; SPORT PRACTICE; CAFFEINE; NICOTINE; DISEASE; OBESITY; ADULTS; MEN
Issue Date
201308
Publisher
KOREAN ACAD MEDICAL SCIENCES
Citation
JOURNAL OF KOREAN MEDICAL SCIENCE, v.28, no.8, pp.1174 - 1180
Abstract
Clinical factors such as tall stature, lean body mass, obstructive sleep apnea, alcohol or caffeine, smoking, endurance sports, and genetic factors are proposed as risk factors for lone atrial fibrillation (LAF). The KORAF (KORean Atrial Fibrillation) study is a retrospective multicenter registry that enrolled 3,570 consecutive atrial fibrillation (AF) patients. Data on risk factors were available for 2,133 patients, of whom 398 (18.7%) were identified as having LAF. In univariate analysis, patients with LAF were more likely to be men (82.4% vs 59.8%, P < 0.001) and current smokers (25.9% vs 15.6%, P < 0.01), alcohol drinkers (55.3% vs 31.2%, P < 0.01) and frequent consumers of caffeinated beverages (> 2 cups/day) (31.7% vs 19.3%, P < 0.01), and have a family history of AF (9.0% vs 2.6%, P < 0.001) than the non-LAF patients. Multivariate analysis showed that male gender (OR, 2.30; 95% CI, 1.61-3.27, P < 0.01), family history of AF (OR, 3.12; 95% CI, 1.91-5.12, P < 0.01), current alcohol use (OR, 2.01; 95% CI, 1.46-2.76, P < 0.01), and frequent caffeinated beverage consumption (OR, 1.66; 95% CI, 1.20-2.29, P < 0.01) were independently associated with LAF. In Korean patients, LAF is more closely associated with male gender, family history of AF, current alcohol and frequent caffeinated beverage consumption than non-LAF.
URI
http://hdl.handle.net/YU.REPOSITORY/29257http://dx.doi.org/10.3346/jkms.2013.28.8.1174
ISSN
1011-8934
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의과대학 > 내과학교실 > Articles
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