Hypoglycemic and hepatoprotective effects of Jerusalem artichoke extracts on streptozotocin-induced diabetic rats

Title
Hypoglycemic and hepatoprotective effects of Jerusalem artichoke extracts on streptozotocin-induced diabetic rats
Author(s)
한기동김한섭
Keywords
OXIDATIVE STRESS; LIVER; L.
Issue Date
201308
Publisher
KOREAN SOCIETY FOOD SCIENCE & TECHNOLOGY-KOSFOST
Citation
FOOD SCIENCE AND BIOTECHNOLOGY, v.22, no.4, pp.1121 - 1124
Abstract
The effects of Jerusalem artichoke (JA) on hypoglycemia and hepatoprotection in streptozotocin (STZ)-induced diabetic rats were investigated. Water extract of Jerusalem artichoke (JAE) reversed the increase in serum glucose levels in STZ-induced diabetic rats. Further, JAE treatment remarkably prevented elevation of serum aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase, and gamma-glutamyl transpeptidase levels in STZ-induced diabetic rats. Treatment with JAE also improved lipid profiles damaged by STZ in the liver by reducing serum levels of triglycerides and total cholesterol. These results suggest that oral administration of JAE may have a potential benefit of ameliorating diabetic symptoms by improving liver damage caused by STZ. This study gives useful information for understanding the anti-diabetic effect of JA.
URI
http://hdl.handle.net/YU.REPOSITORY/29206http://dx.doi.org/10.1007/s10068-013-0192-8
ISSN
1226-7708
Appears in Collections:
자연자원대학 > 식품공학과 > Articles
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE