Callosal Disconnection Syndrome after Corpus Callosum Infarct: A Diffusion Tensor Tractography Study

Title
Callosal Disconnection Syndrome after Corpus Callosum Infarct: A Diffusion Tensor Tractography Study
Author(s)
장성호이준여상석장민철
Keywords
ALIEN HAND SYNDROME; APRAXIA; AGRAPHIA; CHILDREN; LESION; BRAIN
Issue Date
201310
Publisher
ELSEVIER SCIENCE BV
Citation
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, v.22, no.7, pp.E240 - E244
Abstract
We report a patient who presented with callosal disconnection syndrome (CDS) and fiber disconnection on diffusion tensor tractography (DTT) after an infarct of the corpus callosum (CC). A 72-year-old woman presented with manifestations of CDS, including frontal alien hand syndrome (AHS), left agraphia, right hemiparesis, right somatosensory deficit, left neglect, and impaired visual recognition. DTT was performed for the evaluation of CC fibers, followed by comparison with DTT findings of normal subjects. DTT of the normal subject revealed bilateral extension of CC fibers to the frontal, parietal, and occipitotemporal cortices. By contrast, CC fibers of the patient revealed extensive disruption, with the exception of CC fibers passing through the anterior genu and the posterior splenium. The extensive disruption of CC fibers appears to explain the patient's various CDS symptoms. In brief, DTT could be useful for detection of CC lesions in patients with CDS.
URI
http://hdl.handle.net/YU.REPOSITORY/28847http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2012.10.015
ISSN
1052-3057
Appears in Collections:
의과대학 > 재활의학교실 > Articles
의과대학 > 신경과학교실 > Articles
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