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dc.contributor.author김세윤ko
dc.contributor.author권순학[권순학]ko
dc.contributor.author조민현[조민현]ko
dc.contributor.author서혜은[서혜은]ko
dc.date.accessioned2015-12-17T02:32:35Z-
dc.date.available2015-12-17T02:32:35Z-
dc.date.created2015-11-13-
dc.date.issued201204-
dc.identifier.citationJOURNAL OF KOREAN MEDICAL SCIENCE, v.27, no.4, pp.402 - 407-
dc.identifier.issn1011-8934-
dc.identifier.urihttp://hdl.handle.net/YU.REPOSITORY/28573-
dc.identifier.urihttp://dx.doi.org/10.3346/jkms.2012.27.4.402-
dc.description.abstractNeurologic complications of children with influenza A H1N1 2009 pandemic, diagnosed in two consecutive influenza seasons were retrospectively reviewed to seek better outcomes in future outbreaks. Patient demographics, clinical manifestations and neurologic outcomes were reviewed. A total of 1,389 children were diagnosed with influenza A H1N1 by real-time reverse transcriptase-polymerase chain reaction. Of these, 23 (1.7%) patients had neurologic involvement. Their mean age was 5.9 +/- 3.6 yr (range, 6 months to 11 yr) and 16 (69.9%) were boys. None of the 23 patients had been vaccinated for influenza A H1N1 and seasonal influenzas. Twenty-two of the 23 patients presented with seizures. Clinical features included febrile convulsion (n = 19), afebrile convulsion (n = 1), aseptic meningitis (n = 1), encephalopathy (n = 1), and acute necrotizing encephalopathy (n = 1). They all were treated with Oseltamivir twice daily for 5 days immediately after nasal and throat swab testing. Twenty-one of the subjects recovered fully, but the youngest two infants experienced severe neurological sequelae. The results indicate that neurologic complications associated with influenza A H1N1 2009 pandemic were mostly mild, but rarely were serious. Prompt intervention leads to a better outcome and vaccination may prevent the disease, thus staving off serious neurological complications following influenza, especially in young infants.-
dc.language영어-
dc.publisherKOREAN ACAD MEDICAL SCIENCES-
dc.subjectINFLUENZA-A H1N1-
dc.subjectYOUNG-CHILDREN-
dc.subjectINTENSIVE-CARE-
dc.subjectRISK-FACTORS-
dc.subjectENCEPHALOPATHY-
dc.subjectTEXAS-
dc.titleNeurologic Complications and Outcomes of Pandemic (H1N1) 2009 in Korean Children-
dc.typeArticle-
dc.identifier.wosid000302588800011-
dc.identifier.scopusid2-s2.0-84862905778-
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의과대학 > 소아청소년과학교실 > Articles
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