Impact of Total Occlusion of an Infarct-Related Artery on Long-Term Mortality in Acute Non-ST-Elevation Myocardial Infarction Patients Who Underwent Early Percutaneous Coronary Intervention

Title
Impact of Total Occlusion of an Infarct-Related Artery on Long-Term Mortality in Acute Non-ST-Elevation Myocardial Infarction Patients Who Underwent Early Percutaneous Coronary Intervention
Author(s)
김영조김민철[김민철]안영근[안영근]류시현[류시현]정명호[정명호]김주한[김주한]홍영준[홍영준]채성철[채성철]허승호[허승호]성인환[성인환]채재근[채재근]
Keywords
REGISTRY; ANGIOGRAPHY; DEFINITION; RISK
Issue Date
201205
Publisher
INT HEART JOURNAL ASSOC
Citation
INTERNATIONAL HEART JOURNAL, v.53, no.3, pp.160 - 164
Abstract
Some patients with non-ST-elevation myocardial infarction (NSTEMI) have a total occlusive infarct-related artery. However, the long-term prognosis of these patients is uncertain, particularly for those who underwent an early invasive strategy. The aim of this study was to determine the clinical impact of total occlusion (TO) of an infarct-related artery (IRA) in these patients. A total of 2,094 patients with NSTEMI who underwent an early invasive strategy with percutaneous coronary intervention (PCI) in the Korea Acute MI Registry (KAMIR) were analyzed (TO group; 665 patients, and non-TO group; 1,429 patients). In-hospital and one-year clinical outcomes were compared between the two groups. The left circumflex (42.9%) and right coronary artery (31.9%) were the major IRA in the TO group, while the left anterior descending artery was more common as an IRA in the non-TO group (44.1%). En-hospital complications including death and cardiogenic shock occurred frequently in the TO group. Also, the rates of one-month and 12-month adverse cardiac outcomes were higher in the TO group. In the Cox-proportional hazard model, TO in IRA predicted 12-month all-cause death. In conclusion, NSTEMI patients with TO in IRA showed worse short- and long-term clinical outcomes compared with those of non-TO patients. (Int Heart J 2012; 53: 160-164)
URI
http://hdl.handle.net/YU.REPOSITORY/28349
ISSN
1349-2365
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의과대학 > 내과학교실 > Articles
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