Invasive Breast Carcinoma Arising in Microglandular Adenosis: Two Case Reports

Title
Invasive Breast Carcinoma Arising in Microglandular Adenosis: Two Case Reports
Author(s)
배영경최정은
Keywords
ACINIC CELL-CARCINOMA; MAMMARY-CARCINOMA
Issue Date
201312
Publisher
KOREAN BREAST CANCER SOC
Citation
JOURNAL OF BREAST CANCER, v.16, no.4, pp.432 - 437
Abstract
Microglandular adenosis (MGA) is a rare benign disease that shows an infiltrative growth pattern of small glands, and it may progress to include atypia and carcinoma. Here we report two cases of breast carcinoma arising in MGA. Case 1 was a 44-year-old woman with a previous history of ductal carcinoma in situ in her right breast. During a follow-up, a 1.8 cm mass-like lesion was found in her left breast. An excisional biopsy suggested that the lesion was breast carcinoma. Case 2 was a 57-year-old woman with a 2.9 cm mass in her right breast. A core needle biopsy of the lesion suggested invasive carcinoma. Both patients underwent modified radical mastectomy with sentinel lymph node biopsy. Both tumors lacked a myoepithelial cell layer and stained positively for S-100, lysozyme, and alpha 1-antitrypsin, which is typical of MGA. Both cases showed invasive carcinoma arising in MGA.
URI
http://hdl.handle.net/YU.REPOSITORY/28310http://dx.doi.org/10.4048/jbc.2013.16.4.432
ISSN
1738-6756
Appears in Collections:
의과대학 > 병리학교실 > Articles
의과대학 > 성형외과학교실 > Articles
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