Clinical outcomes of elective single morula embryo transfer versus elective single blastocyst embryo transfer in IVF-ET

Title
Clinical outcomes of elective single morula embryo transfer versus elective single blastocyst embryo transfer in IVF-ET
Author(s)
고민환강상민[강상민]이상원[이상원]정학준[정학준]윤산현[윤산현]임진호[임진호]이성구[이성구]
Keywords
IN-VITRO FERTILIZATION; INTRACYTOPLASMIC SPERM INJECTION; TWIN PREGNANCIES; STAGE; DECREASES; DIAGNOSIS; CYCLES; FRESH; WOMEN; TRIAL
Issue Date
201205
Publisher
SPRINGER/PLENUM PUBLISHERS
Citation
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, v.29, no.5, pp.423 - 428
Abstract
To compare the clinical outcomes of elective single morula embryo transfer (eSMET) versus elective single blastocyst embryo transfer (eSBET) in selected patients. This study was a retrospective study which analyzed for 271 cycles in women under 37 years of age who are undergoing their first or second trial of in vitro fertilization-embryo transfer (IVF-ET) from January 2008 to December 2009. The eSMET was performed on day 4 ( = 130) and the eSBET was conducted on day 5 ( = 141). The clinical pregnancy rate (51.5% vs. 51.8%, = 0.97), implantation rate (52.3% vs. 52.5%, = 0.98), and live birth rate (39.2% vs. 44.7%, = 0.36) were similar in the eSMET and eSBET groups, respectively. The miscarriage rate of the eSMET group (23.9%) was slightly higher than that of the eSBET group (13.7%) ( = 0.12), without reaching statistical significance. There was only one case of monozygotic twin pregnancy in each group. The clinical outcomes of day 4 eSMET were comparable to those of day 5 eSBET. Therefore, day 4 eSMET is a viable option or an alternative to day 5 eSBET, with no difference in success rates.
URI
http://hdl.handle.net/YU.REPOSITORY/28276http://dx.doi.org/10.1007/s10815-012-9736-8
ISSN
1058-0468
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의과대학 > 산부인과학교실 > Articles
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