Validation of the Edmonton Symptom Assessment System in Korean Patients With Cancer

Title
Validation of the Edmonton Symptom Assessment System in Korean Patients With Cancer
Author(s)
이경희남성현[남성현]권정혜[권정혜]고수진[고수진]신상원[신상원]원지윤[원지윤]윤소영[윤소영]홍영선[홍영선]Eduardo Bruera[Eduardo Bruera]박경우[박경우]
Keywords
PALLIATIVE CARE; ASSESSMENT SCALE; DEPRESSION; ANXIETY; ESAS; INVENTORY; VERSION
Issue Date
201312
Publisher
ELSEVIER SCIENCE INC
Citation
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, v.46, no.6, pp.947 - 956
Abstract
Context. The Edmonton Symptom Assessment System (ESAS) is a brief, widely adopted, multidimensional questionnaire to evaluate patient-reported symptoms. Objectives. To develop a Korean version of the ESAS (K-ESAS) and to perform a psychometric analysis in Korean patients with advanced cancer. Methods. We tested the K-ESAS in two pilot studies with 15 patients each. We assessed internal consistency, test-retest reliability, and concurrent validity in 163 Korean patients, who completed the K-ESAS along with the Korean versions of the M. D. Anderson Symptom Inventory (K-MDASI) and the Hospital Anxiety and Depression Scale (K-HADS) twice. A total of 38 patients completed the questionnaires again seven days later to assess responsiveness. Results. The K-ESAS scores had good internal consistency, with a Cronbach's alpha coefficient of 0.88, indicating that no questions had undue influence on the score. Pearson correlation coefficients for K-ESAS symptom scores between baseline and after two to four hours ranged from 0.72 (95% CI 0.64-0.79) to 0.87 (95% CI 0.82-0.90), indicating strong test-retest reliability. For concurrent validity, Pearson correlation coefficients between K-ESAS symptom scores and corresponding K-MDASI symptom scores ranged from 0.70 (95% CI 0.62-0.77) to 0.83 (95% CI 0.77-0.87), indicating good concurrent validity. For the K-HADS, concurrent validity was good for anxiety (r = 0.73, 95% CI 0.65-0.79) but moderate for depression (r = 0.4, 95% CI 0.26-0.52). For responsiveness, changes in K-ESAS scores after seven days were moderately correlated with changes in K-MDASI scores but weakly correlated with changes in K-HADS scores. Conclusion. The K-ESAS is a valid and reliable tool for measuring multidimensional symptoms in Korean patients with cancer. (C) 2013 U. S. Cancer Pain Relief Committee. Published by Elsevier Inc. All rights reserved.
URI
http://hdl.handle.net/YU.REPOSITORY/28268http://dx.doi.org/10.1016/j.jpainsymman.2013.01.012
ISSN
0885-3924
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의과대학 > 내과학교실 > Articles
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