Extranodal Follicular Dendritic Cell Sarcoma with Rapid Growth in Parapharynx: A Case Report

Title
Extranodal Follicular Dendritic Cell Sarcoma with Rapid Growth in Parapharynx: A Case Report
Author(s)
최준혁김동훈[김동훈]표정수[표정수]강구현[강구현]도성임[도성임]채성완[채성완]최윤라[최윤라]손진희[손진희]김경근[김경근]이상혁[이상혁]
Keywords
PHARYNGEAL REGION; TUMOR; FEATURES; HEAD
Issue Date
201206
Publisher
KOREAN SOCIETY PATHOLOGISTS
Citation
KOREAN JOURNAL OF PATHOLOGY, v.46, no.3, pp.306 - 310
Abstract
Follicular dendritic cell sarcoma (FDCS) is a rare malignancy arising from the antigen-presenting cells in the lymph node and extranodal tissue. We describe a 31-year-old male patient who presented with a swelling of the left parapharynx. The radiologic findings showed a 4.7x4.5x1.9 cm-sized, ill-defined mass in the left parapharyngeal space. A fine-needle aspiration cytology was performed and it showed scattered, irregular, cohesive clusters of tumor cells with a spindle-to-ovoid shape with irregular contours in a background of lymphocytes. Based on these findings, a diagnosis of spindle cell neoplasm was made. The surgically resected tumor was composed of elongated, ovoid or polygonal cells showing positive immunohistochemistry for CD21, CD23, and CD35. Postoperatively, the residual tumor was observed to undergo a rapidly growth. There is an overlap in the cytologic and histologic findings between FDCS of the parapharynx and other tumors. Pathologists should therefore be aware of its characteristics not only to provide an accurate diagnosis but also to recommend the appropriate clinical management.
URI
http://hdl.handle.net/YU.REPOSITORY/28102http://dx.doi.org/10.4132/KoreanJPathol.2012.46.3.306
ISSN
1738-1843
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의과대학 > 병리학교실 > Articles
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