omega-Transaminases for the Production of Optically Pure Amines and Unnatural Amino Acids

Title
omega-Transaminases for the Production of Optically Pure Amines and Unnatural Amino Acids
Author(s)
윤형돈샘매튜[샘매튜]
Keywords
DYNAMIC KINETIC RESOLUTION; ASYMMETRIC-SYNTHESIS; CHIRAL AMINES; DIRECTED EVOLUTION; ALPHA-METHYLBENZYLAMINE; SUBSTRATE-SPECIFICITY; RATIONAL DESIGN; ENZYME STABILITY; ORGANIC-SOLVENTS; (S)-AMINO ACIDS
Issue Date
201206
Publisher
AMER CHEMICAL SOC
Citation
ACS CATALYSIS, v.2, no.6, pp.993 - 1001
Abstract
omega-Transaminases have been increasingly used as efficient biocatalysts due to their ability to produce a wide range of optically pure amine compounds. Several approaches have been adopted, including screening, engineering, and development of new techniques in reaction systems for different aspects of the enzymes. This review summarizes the various methodologies and approaches adopted to produce enantiomerically pure amines and unnatural amino acids using omega-transaminases.
URI
http://hdl.handle.net/YU.REPOSITORY/28003http://dx.doi.org/10.1021/cs300116n
ISSN
2155-5435
Appears in Collections:
생명공학부 > 생명공학부 > Articles
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