Alveolar Soft Part Sarcoma Metastasized to Both the Skull and the Brain

Title
Alveolar Soft Part Sarcoma Metastasized to Both the Skull and the Brain
Author(s)
김민수신태희[신태희]정영진김오룡
Keywords
MANAGEMENT; TFE3; GENE
Issue Date
201207
Publisher
KOREAN NEUROSURGICAL SOC
Citation
JOURNAL OF KOREAN NEUROSURGICAL SOCIETY, v.52, no.1, pp.55 - 57
Abstract
Alveolar soft part sarcoma (ASPS) with skull and brain metastases is extremely rare. A 53-year-old patient diagnosed as skull metastasis of ASPS visited our clinic complaining of an outgrowing scalp mass in spite of radiation therapy. Past medical history revealed that the patient had been diagnosed and treated for ASPS of the thigh 4 years ago. Magnetic resonance imaging revealed a hyperintense ovoid mass on the T2-weighted image, an isointense on the T1-weighted image, and a homogeneous enhanced mass with gadolinium. Another small-sized enhanced mass with mild peritumoral swelling was found at the deep white matter of the left frontal lobe. A gross total resection of the skull lesion with cranioplasty was performed for the surgical defect. A histologic examination of the specimens revealed metastatic ASPS involving the skull. Surgery with a total removal of the lesions may be effective for improving a patient's symptoms especially from neurological dysfunction.
URI
http://hdl.handle.net/YU.REPOSITORY/27677http://dx.doi.org/10.3340/jkns.2012.52.1.55
ISSN
2005-3711
Appears in Collections:
의과대학 > 신경외과학교실 > Articles
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